Penfield Addiction Ministries collaborates with several reputable organizations to enhance their recovery programs. This includes partnerships with the Georgia Department of Community Health, ensuring compliance with health regulations and standards.

They are also supported by the National Institute on Drug Abuse, which provides access to the latest research and best practices in addiction science. Furthermore, affiliations with the Georgia Baptist Mission Board and Georgia Baptist Association connect them with faith-based community resources, while the Georgia Association of Recovery Residences helps uphold high standards in residential care for recovery.